What is the anti-dsDNA Test?

The Anti-dsDNA (Double-Stranded DNA Antibody) Test detects antibodies directed against the body’s own DNA. These antibodies are strongly associated with Systemic Lupus Erythematosus (SLE) and are useful for both diagnosis and disease monitoring.

Why is the Anti-dsDNA Test Done?

Doctors may recommend this test to:

• Help diagnose Systemic Lupus Erythematosus (SLE)
• Confirm autoimmune disease after a positive ANA test
• Monitor lupus disease activity
• Assess the risk of lupus-related kidney involvement (Lupus Nephritis)
• Evaluate response to treatment

When Should You Get This Test?

Your doctor may advise the test if you have symptoms such as:

• Joint pain and swelling
• Persistent fatigue
• Skin rashes (especially butterfly rash)
• Fever without infection
• Hair loss
• Mouth ulcers
• Chest pain
• Kidney-related symptoms
• Unexplained inflammation

Who Should Get an Anti-dsDNA Test?

This test is recommended for:

• Patients with a positive ANA test
• Individuals suspected of having lupus
• Patients diagnosed with SLE for disease monitoring
• People with autoimmune disease symptoms
• Patients with suspected lupus nephritis

Test Preparation

• Fasting is not required
• Drink normal amounts of water
• Continue medications unless your doctor advises otherwise

Sample Required

• Blood (Serum)

Report Delivery

Reports are generally available within 24–48 hours.

Understanding Your Results

Your report may be:

• Negative: Anti-dsDNA antibodies not detected.
• Positive: Anti-dsDNA antibodies detected, which may support a diagnosis of SLE when interpreted with symptoms and other laboratory findings.
• Higher antibody levels can be associated with increased lupus disease activity, particularly kidney involvement.

Note: Test results should always be interpreted by a qualified healthcare professional along with your clinical history and other investigations.

Benefits of Testing at HAD LABS

• NABL Accredited Laboratory
• Accurate & Reliable Results
• Experienced Laboratory Professionals
• Home Sample Collection Available
• Fast Report Delivery
• Affordable Pricing
• Quality Assured Testing

Frequently Asked Questions (FAQs)

Is fasting required for the Anti-dsDNA Test?

No. Fasting is not required.

What sample is used for this test?

A blood sample is collected from a vein in your arm.

Can I book a home sample collection?

Yes. HAD LABS provides home sample collection services.

Is Anti-dsDNA the same as an ANA test?

No. ANA is a screening test for autoimmune diseases, while Anti-dsDNA is a more specific test that helps diagnose and monitor Systemic Lupus Erythematosus (SLE).

Can this test diagnose lupus on its own?

No. It is one part of the evaluation. Your doctor will interpret the results along with your symptoms, examination, and other laboratory tests.

Why Choose HAD LABS?

• NABL Accredited Laboratory
• Advanced Diagnostic Technology
• Trusted & Accurate Testing
• Home Sample Collection
• Fast Turnaround Time
• Affordable Prices
• Professional Customer Support